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Procollagen I of Aminoterminal Propeptide（PINP)for Automatic immunoassay analyzer in Bone Metabolism

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Procollagen I of Aminoterminal Propeptide（PINP)for Automatic immunoassay analyzer in Bone Metabolism

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Brand Name : Zecen

Model Number : CLIA PINP

Certification : CE, ISO13485

Place of Origin : China

MOQ : 10 boxes

Payment Terms : L/C, D/A, D/P, T/T, Western Union, MoneyGram

Supply Ability : 5000 Set/Sets per Month

Delivery Time : 15 workdays

Packaging Details : Carton package

Name : PINP

Analyzer : CIA series

Principle : CLIA

Recalibration : 2-points

Storage : 2-8°C

Material : Magnetic beads, calibrators, Anti A/B, control1/2

Validity period : 18 months

Precision : ≤8%

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Procollagen I of Aminoterminal Propeptide(PINP)for Automatic immunoassay analyzer in Bone Metabolism

Test item PINP
Specification 100 Test/Box for CIA series
24 Test/Box for POCT
Principle

  • sandwich method
Component Magnetic Beads
Calibrator Low
Calibrator High
PINP Anti
Control 1
Control 2
Accessories Required But Not Provided Substrate
Washing solution
Sample material serum
Sample volume More than 200μL
Storage 2-8℃

Procollagen I of Aminoterminal Propeptide（PINP)for Automatic immunoassay analyzer in Bone Metabolism

Procollagen I of Aminoterminal Propeptide（PINP)for Automatic immunoassay analyzer in Bone Metabolism

Procollagen I of Aminoterminal Propeptide（PINP)for Automatic immunoassay analyzer in Bone Metabolism

Bone type I collagen is the most abundant form of collagen in the body, comprising approximately 90% of bone mass.

Type I collagen is mainly synthesized in bone tissue. Procollagen is synthesized first. There is an extension peptide at the amino N-terminus and C-terminus of type I procollagen, which are respectively called Type I procollagen N-terminal propeptide (PINP). and type I procollagen C-terminal propeptide (PICP); when type I procollagen is secreted out of the cell by osteoblasts, the N-terminal and C-terminal extended peptides are cleaved by proteases, and in addition to a small amount deposited in the bone matrix, a large amount of It enters the blood circulation and is eventually metabolized and eliminated by the liver. Therefore, under the exclusion of liver disease, the detection of PINP content in blood can accurately reflect the activity of osteoblasts, which in turn reflects the intensity of bone metabolism in the body, and guides the diagnosis and treatment of diseases caused by abnormal bone metabolism.


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